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MIRZA


Target Prediction


Analysis Scheme:
A rigorous biophysical model of miRNA-target interaction and infer its energy parameters from Ago-CLIP data. The model includes parameters associated with base pairs and loops and specific miRNA position–dependent energy parameters that reflect the constraints imposed by the Argonaute protein on miRNA-mRNA interaction.

Homepage: Link

Last Software Update: Jan. 30, 2015
Publication Date: Jan. 20, 2013
Reference: [Journal] [Pubmed] [CrossRef]
Citations: 77 [via Pubmed]

Organism Specific:
  • human

    • Reference Genome Needed:
    Online/Local: /
    Installation/User Level: intermediate (local)
    User Adjustability:
    User support:
    Precomputed Target Results Available For Download:
    License: GPLv3
    Target Prediction
    Algorithm Features:
  • seed match
  • free energy
  • 3' compensatory pairing
  • G:U pairs allowed in the seed
  • miRNA expression (needed)

    • Target Region: 3' UTR
    Target Annotation:
    NGS Data Needed:
    Metaserver:





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