miRanda algorithm is based on a comparisone of miRNAs complementarity to 3'UTR regions. The binding energy of the duplex structure, evolutionary conservation of the whole target site and its position within 3”UTR are calculated and account for a final result which is a weighted soum of match and mismatch scores for base pairs and gap penalties.
Last Software Update: Aug. 25, 2010
Publication Date: Oct. 5, 2004
Citations: 1472 [via Pubmed]
Reference Genome Needed:
Installation/User Level: easy
Precomputed Target Results Available For Download: (human, mouse, rat, worm, fly)
Performance : Sensitivity: 49%, Precision: 29%