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mBISON calculates the significance of over-representation of miRNA targets in a given non-ranked gene set. The gene set can be specified either by a list of genes or by one or more ChIP-seq datasets followed by a user-defined peak-gene association procedure. mBISON is based on predictions from TargetScan and uses a randomization step to calculate False-Discovery-Rates for each miRNA, including a correction for gene set specific properties such as 3’UTR length.

Homepage: Link

Last Software Update: April 16, 2015
Publication Date: April 16, 2015
Citations: 1 [via Pubmed]

Organism Specific:
  • human
  • mouse

  • Reference Genome Needed:
    Online/Local: /
    Installation/User Level: easy
    User Adjustability:
    User support:
    Precomputed Target Results Available For Download:
    Algorithm: random sampling, Benjamini-Hochberg multiple-testing correction
    Input Data Required:
  • list of genes IDs
  • ChIP-seq datasets in bed-format supplying genomic positions (max. 3)

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