Overview
Tools4miRs is a first, manually curated platform gathering at the present over 170 methods for the broadly-defined miRNA analysis. All tools in Tools4miRs are classified in the four general and seven more detailed categories. In each of the aforementioned sections user can additionally filter available methods according to his research needs, capabilities and preferences. Beside basic summary seen at first glance, the user can get detailed information concerning each tool. Tools4miRs is also a web-based target prediction meta-server incorporating user-designated target prediction methods in the analysis of user-provided data. Results generated by described meta-server can be presented in basic and extended form, while user can can additionally filter them using Union, Intersection or Consensus method. Tools4miRs is free, open-access service which will be systematically updated.
miRNA Biogenesis and Function
Concept, Design, Animation: Katharina Petsche
Citing / References
If you found Tools4miRs.org useful for your work, please cite us!
Lukasik A, Wójcikowski M, Zielenkiewicz P.
Tools4miRs – one place to gather all the tools for miRNA analysis. Bioinformatics. 2016;
doi:10.1093/bioinformatics/btw189
Statistics
Tools4miRs v.1.1Number of tools: 175Last update: Oct. 22, 2024, midnight
Latest Literature
- RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes. Shen Q, Wang YE, Truong M, Mahadevan K, Wu JJ, Zhang H, Li J, Smith HW, Smibert CA, Palazzo AF PLoS Genet. 2021 Feb 18;17(2):e1009378 Pubmed >>
- MicroRNA-545 suppresses progression of ovarian cancer through mediating PLK1 expression by a direct binding and an indirect regulation involving KDM4B-mediated demethylation. Zhang H, Zhang K, Xu Z, Chen Z, Wang Q, Wang C, Cui J BMC Cancer. 2021 Feb 15;21(1):163 Pubmed >>
- microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP. Zhang X, Chapat C, Wang P, Choi JH, Li Q, Luo J, Wiebe S, Kim SH, Robichaud N, Karam IF, Dai D, Hackett AP, Lin R, Alain T, Yang L, Jafarnejad SM, Sonenberg N Mol Cell. 2021 Feb 09;: Pubmed >>
- Molecular insights into miRNA processing by Arabidopsis thaliana SERRATE. Nucleic Acids Res. 2021 Feb 12;: Pubmed >>
- miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer. Ben-Elazar S, Aure MR, Jonsdottir K, Leivonen SK, Kristensen VN, Janssen EAM, Kleivi Sahlberg K, Lingjærde OC, Yakhini Z PLoS Comput Biol. 2021 Feb 10;17(2):e1008608 Pubmed >>
- Novel roles of an intragenic G-quadruplex in controlling microRNA expression and cardiac function. Zhu M, Gao J, Lin XJ, Gong YY, Qi YC, Ma YL, Song YX, Tan W, Li FY, Ye M, Gong J, Cui QH, Huang ZH, Zhang YY, Wang XJ, Lan F, Wang SQ, Yuan G, Feng Y, Xu M Nucleic Acids Res. 2021 Feb 09;: Pubmed >>
- Impact of gestational low-protein intake on embryonic kidney microRNA expression and in nephron progenitor cells of the male fetus. Sene LB, Scarano WR, Zapparoli A, Gontijo JAR, Boer PA PLoS One. 2021;16(2):e0246289 Pubmed >>
- Development and use of miRNA-derived SSR markers for the study of genetic diversity, population structure, and characterization of genotypes for breeding heat tolerant wheat varieties. Tyagi S, Kumar A, Gautam T, Pandey R, Rustgi S, Mir RR PLoS One. 2021;16(2):e0231063 Pubmed >>
- Correction to: MicroRNA-99a induces G1-phase cell cycle arrest and suppresses tumorigenicity in renal cell carcinoma. Cui L, Zhou H, Zhao H, Zhou Y, Xu R, Xu X, Zheng L, Xue Z, Xia W, Zhang B, Ding T, Cao Y, Tian Z, Shi Q, He X BMC Cancer. 2021 Jan 29;21(1):103 Pubmed >>
- Circulating exosomal microRNA expression patterns distinguish cardiac sarcoidosis from myocardial ischemia. Crouser ED, Julian MW, Bicer S, Ghai V, Kim TK, Maier LA, Gillespie M, Hamzeh NY, Wang K PLoS One. 2021;16(1):e0246083 Pubmed >>
- To Degrade a MicroRNA, Destroy Its Argonaute Protein. Wu PH, Zamore PD Mol Cell. 2021 Jan 21;81(2):223-225 Pubmed >>
- Deciphering the miRNA transcriptome of breast muscle from the embryonic to post-hatching periods in chickens. Liu J, Li F, Hu X, Cao D, Liu W, Han H, Zhou Y, Lei Q BMC Genomics. 2021 Jan 19;22(1):64 Pubmed >>
- Integrated analysis of mRNA and miRNA profiles revealed the role of miR-193 and miR-210 as potential regulatory biomarkers in different molecular subtypes of breast cancer. Evangelista AF, Oliveira RJ, O Silva VA, D C Vieira RA, Reis RM, C Marques MM BMC Cancer. 2021 Jan 18;21(1):76 Pubmed >>
- Prognostic value of low microRNA-34a expression in human gastrointestinal cancer: a systematic review and meta-analysis. Chen YL, Liu XL, Li L BMC Cancer. 2021 Jan 14;21(1):63 Pubmed >>
- A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms. Zhou L, Miller C, Miraglia LJ, Romero A, Mure LS, Panda S, Kay SA Proc Natl Acad Sci U S A. 2021 Jan 05;118(1): Pubmed >>
- Integrated analysis of the responses of a circRNA-miRNA-mRNA ceRNA network to heat stress in rainbow trout (Oncorhynchus mykiss) liver. Quan J, Kang Y, Luo Z, Zhao G, Li L, Liu Z BMC Genomics. 2021 Jan 11;22(1):48 Pubmed >>
- Identification of a novel six autophagy-related genes signature for the prognostic and a miRNA-related autophagy predictor for anti-PD-1 therapy responses in prostate cancer. Wu L, Quan W, Yue G, Luo Q, Peng D, Pan Y, Zhang G BMC Cancer. 2021 Jan 05;21(1):15 Pubmed >>
- Widespread occurrence of microRNA-mediated target cleavage on membrane-bound polysomes. Yang X, You C, Wang X, Gao L, Mo B, Liu L, Chen X Genome Biol. 2021 Jan 05;22(1):15 Pubmed >>
- Phase-related differences in egg production of the migratory locust regulated by differential oosorption through microRNA-34 targeting activinβ. Zhao L, Guo W, Jiang F, He J, Liu H, Song J, Yu D, Kang L PLoS Genet. 2021 Jan;17(1):e1009174 Pubmed >>
- A pan-cancer atlas of somatic mutations in miRNA biogenesis genes. Galka-Marciniak P, Urbanek-Trzeciak MO, Nawrocka PM, Kozlowski P Nucleic Acids Res. 2021 Jan 06;: Pubmed >>